<HTML><BODY style="word-wrap: break-word; -khtml-nbsp-mode: space; -khtml-line-break: after-white-space; "><DIV>Dear Dr Dubner and Dr Schapachnik</DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV>I have also questions to some authors as Dr Fontaine and Dr Hammill</DIV><DIV>Some things seem very simple: tachycardia or syncope is of benign prognosis if there is no underlying heart disease. The significance completely changes in association with heart disease.</DIV><DIV>However with the development of magnetic resonance imaging (MRI) or similar techniques, many of patients have signs of heart disease not visible at echocardiography as myocardial scar in VT, signs of ARVD in right outflow tract tachycardia, signs of beginning DCM..... A benign VT becomes a tachycardia with a risk of SD??</DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV>Is RMI necessary in all patients with VT or syncope and with apparently normal echocardiography? </DIV><DIV>Does abnormal RMI in asymptomatic patient with only VPB's need others investigations, preventive beta-blocker therapy or more?? </DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV>To my opinion, the cardiology becomes more and more difficult. We have learned many important data in cardiology through small studies of one or several authors; now we learn some data after very large multicentric studies engaged by big companies with the very well known problem of the criteria of exclusion and inclusion. Where is my patient?</DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV>Pardon my difficulties in the real life and thank you for your recommendation.</DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV>Béatrice Brembilla-Perrot</DIV><BR><DIV> <SPAN class="Apple-style-span" style="border-collapse: separate; border-spacing: 0px 0px; color: rgb(0, 0, 0); font-family: Helvetica; font-size: 12px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; text-align: auto; -khtml-text-decorations-in-effect: none; text-indent: 0px; -apple-text-size-adjust: auto; text-transform: none; orphans: 2; white-space: normal; widows: 2; word-spacing: 0px; "><DIV style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; ">--</DIV><DIV style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; ">Dr.<SPAN class="Apple-converted-space"> </SPAN>Sergio<SPAN class="Apple-converted-space"> </SPAN>Dubner</DIV><DIV style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; ">President<SPAN class="Apple-converted-space"> </SPAN>of<SPAN class="Apple-converted-space"> </SPAN>Scientific<SPAN class="Apple-converted-space"> </SPAN>Committee</DIV><DIV style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; font: normal normal normal 13px/normal Lucida Grande; min-height: 16px; ; font-family: Lucida Grande; font-size: 13px; "><BR style="font-family: Lucida Grande; font-size: 13px; "></DIV><DIV style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; ">Dr.<SPAN class="Apple-converted-space"> </SPAN>Edgardo<SPAN class="Apple-converted-space"> </SPAN>Schapachnik</DIV><DIV style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; ">President<SPAN class="Apple-converted-space"> </SPAN>of<SPAN class="Apple-converted-space"> </SPAN>Steering<SPAN class="Apple-converted-space"> </SPAN>Committee</DIV><DIV><BR class="khtml-block-placeholder"></DIV><DIV><BR class="khtml-block-placeholder"></DIV><BR class="Apple-interchange-newline"></SPAN> </DIV><BR></BODY></HTML>