[SCD-FORUM] 12 RE:一例长QT综合征患儿-- Makarov 医师

[SCD Symposium]

根据我们对先天性长QT综合征患儿的治疗和随访经 
验，β受体阻滞剂（如普萘洛尔、阿替洛尔、纳多洛 
尔）日剂量1-2 mg/kg，不会显著增加这些患儿心动过缓 
的发生率。有时候联合应用常规剂量(1 mg/kg)的β受体 
阻滞剂和钠通道阻断剂（卡马西平 10 mg/kg/d ）可能有 
效。但在此病例中，患儿出现晕厥，QTc非常长(600  
ms)，静息心电图中出现对5岁儿童来说非常慢的55次/ 
分的心率。我个人认为这类患儿需要植入抗心律失常 
装置并联合药物治疗。

Leonid Makarov博士

Moscow Institute pediatry and children surgery

Moscow, Russia. Taldomskaya str. 2

leo at oss.ru



Sergio Dubner博士

科委会主席

Edgardo Schapachnik博士

组委会主席

白英楠译 王玲洁校

12E RE: A children with LQTS. Dr. Makarov

By our experience of the managment and follow up of children with    
Congenital     LQTS, beta blockers (Propranolol, Atenolol, Nadolol)  
therapy in daily   dose  1-2 mg/kg not significantly increase of  
bradycardia in this pts.   Sometimes  combination of the regular  
doses of betablockers (1 mg/kg) and Na   blockers (we use  
carbamazepin 10 mg/kg/daily) may be useful. But in this case    
Patient  had syncope, very long QTc (600 ms) and heart rate 55 bpm  
for 5 years   old    children on rest ECG  is very low.  By my  
opinion children need in antyarhythmic device in combination with  
drug therapy.

  Dr. Leonid Makarov     Leonid Makarov

Moscow Institute pediatry and children surgery

Moscow, Russia. Taldomskaya str. 2

leo at oss.ru

  --

Dr. Sergio Dubner
President of Scientific Committee

Dr. Edgardo Schapachnik
President of Steering Committee