[AF-FORUM] 181E FA é uma doença ou sindrome? Dr. Perez Riera

[ATRIAL FIBRILLATION SYMPOSIUM]

Então se a síndrome é uma situação com sintomas definidos e de causa não 
conhecida porque chamar-la de síndrome de Brugada se conhecemos a causa 
genética.
Concluímos que é necessário mudar de categoria de síndrome  para doença

Thank in advance
All the best
Andrés Ricardo Pérez Riera MD. In Charge of electro-vectorcardiogram sector.
Cardiology Discipline. ABC Medical Faculty.  ABC Foundation. Santo André -
São Paulo. Brazil
Sebastião Afonso, 885     CEP: 04417-000
Jardim Miriam – São Paulo - Brazil
Phone: (11) 5621-2390
riera em uol.com.br

> There is disease and signs of disease and its symptoms. The symptoms are
> gathered according to key characteristics. The disease is always a 
> union of
> syndromes: syndromes at the level of the organism, related to typical
> pathological process(es) and with a general reaction of the organism 
> (e.g.,
> adaptation syndrome, analogous to H. Selye distress); syndromes at local
> level, related to typical pathological process(es) and related to 
> functional
> alterations of the organ involved in the pathological process.
> As to point 1) “know etiological agent” and point 2) “identified genetic
> defect”; I see no difference between them, since point 2 is included 
> in point
> 1 (when a genetic defect is the etiology). Points 1 and 2 are related 
> to the
> necessary condition to define the disease, i.e. the origin of the 
> pathological
> findings of the patient. About point 3) “Set of characteristic signs and
> symptoms or compatible anatomic alterations”, these are the symptoms 
> and/or
> syndromes. The combination of points 1 and 2 with points 3 and 4) “A
> combination of the previous items” mean the necessary (etiology) and
> sufficient (clinical signs) for a disease. Then, without etiology and
> symptoms, there is no disease. The syndrome is a situation when a set of
> related symptoms has been defined, but the cause is unknown. If we have
> an “AF” syndrome, with unknown etiology, then it is an idiopathic or 
> essential
> AF.
>
> Dr. Mykola Iabluchansky
>
>